Blar i ODA Open Digital Archive på forfatter "Sandvig, Kirsten"
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Biodistribution, pharmacokinetics and excretion studies of intravenously injected nanoparticles and extracellular vesicles: Possibilities and challenges
Skotland, Tore; Iversen, Tore Geir; Llorente, Alicia; Sandvig, Kirsten (Advanced Drug Delivery Reviews;Volume 186, July 2022, 114326, Peer reviewed; Journal article, 2022-05-21)There is a large interest in developing nanoparticles and extracellular vesicles for delivery of therapeutics or imaging agents. Regulatory approval of such products requires knowledge about their biodistribution, metabolism ... -
siRNA screening reveals that SNAP29 contributes to exosome release
Hessvik, Nina Pettersen; Sagini, Krizia; Romero, Silvana Angelica Troncoso; Ramirez, Manuel; Rodriguez, Marta; Tutturen, Astrid Elisabeth Voorham; Kvalvaag, Audun Sverre Myrset; Stang, Espen; Brech, Andreas; Sandvig, Kirsten; Llorente, Alicia (Peer reviewed; Journal article, 2023)Cells release extracellular vesicles (EVs) of different sizes. Small EVs (< 200 nm) can originate from the fusion of multive- sicular bodies with the plasma membrane, i.e. exosomes, and from budding of the plasma membrane, ...